🎉 CELEBRATING 5 YEARS 🎉
5 years of advancing automated cell type annotation

A platform for automatic cell type annotation

Fast and accurate cell type prediction at scale using our knowledgebase, proprietary algorithms and user-friendly interface.
CellKb Interface
High-quality in-built reference
CellKb Results
Marker based annotation
CellKb Analysis
Granular cell type predictions
CellKb Disease Analysis
Cross-species search
🎉 CELEBRATING 5 YEARS 🎉
5 years of advancing automated cell type annotation

A platform for automatic cell type annotation

Fast and accurate cell type prediction at scale using our knowledgebase, proprietary algorithms and user-friendly interface.
Cluster Annotation

Upload cluster-specific gene lists and get cell type predictions using our proprietary rank-based comparison against all signatures in our database.

Annotate clusters in seconds
Matching signatures & publications
Broad & granular predictions
REST API access available
Input:
Cluster Gene avg_log2FC pct.1
1 CCR7 0.985 0.699
1 SELL 0.858 0.801
1 TCF7 0.844 0.673
...
↓
Result:
CellKb cluster annotation results showing hierarchical cell type predictions with scores
Single-Cell & Spatial Annotation
Single-Cell Annotation

Annotate individual cells without clustering requirements using direct cell-to-signature matching.

Input: Raw or processed scRNA-seq data
Method: No clustering step required
Types: Broad and granular classifications
Capacity: Up to 500K cells per analysis
Spatial Deconvolution

Assign cell types in spatial RNA-seq with location-specific analysis using our comprehensive reference database.

Platforms: Visium, Visium HD, Xenium, Custom
Output: Per-spot cell type assignments
Precision: Up to 3 cell types per spot
Cross-species analysis: Human, mouse, and other species
Specialized Tools
Bulk Enrichment

Analyze cell type abundance changes in bulk RNA-seq datasets using gene expression patterns and cell type specificity scores.

Input: Gene lists with fold changes or expression values
Method: Gene specificity analysis using CellKb signatures
Results: Cell type enrichment and depletion detection
Consensus Signatures

Access reliable cell type marker genes validated across multiple independent studies and datasets.

Source: 100K+ cell type signatures from published studies
Method: Cell type specificity analysis for all genes
Context: Species, tissue, disease specific
Biomarker Discovery

Compare cell type signatures across conditions to identify disease-specific biomarkers and therapeutic targets.

Method: Comparative signature analysis
Focus: Disease and normal state biomarkers
Results: Top 10 ranked markers with significance

Included with All Methods

Prediction Scores
Canonical Markers
Statistical Tests